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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
REL
All Species:
9.09
Human Site:
S274
Identified Species:
20
UniProt:
Q04864
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q04864
NP_002899.1
619
68520
S274
S
D
Q
E
V
S
E
S
M
D
F
R
Y
L
P
Chimpanzee
Pan troglodytes
XP_001159537
619
68348
S274
S
D
Q
E
V
S
E
S
M
D
F
R
Y
L
P
Rhesus Macaque
Macaca mulatta
XP_001115312
619
68464
S274
S
D
Q
E
V
S
E
S
M
D
F
R
Y
L
P
Dog
Lupus familis
XP_531836
593
65808
P247
V
A
I
V
F
K
T
P
P
Y
C
R
A
I
T
Cat
Felis silvestris
Mouse
Mus musculus
P15307
587
64942
I242
D
V
H
R
Q
V
A
I
V
F
K
T
P
P
Y
Rat
Rattus norvegicus
NP_954888
550
60249
L207
N
R
N
S
G
S
C
L
G
G
D
E
I
F
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512346
573
64146
F227
K
D
D
I
E
V
R
F
V
L
N
D
W
E
A
Chicken
Gallus gallus
P16236
598
66829
P255
F
L
R
D
I
T
E
P
I
T
V
K
M
Q
L
Frog
Xenopus laevis
Q04865
527
59040
N186
V
S
Q
P
I
Y
D
N
R
A
P
N
T
A
E
Zebra Danio
Brachydanio rerio
NP_001001841
596
67208
F241
T
W
E
A
K
G
S
F
S
Q
A
D
V
H
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P15330
999
111533
A483
H
I
P
E
D
M
E
A
A
D
A
H
A
E
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
97.7
81.7
N.A.
71.2
38.6
N.A.
59.6
49.4
41.8
44.5
N.A.
25.5
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
98.3
86.4
N.A.
79.6
54.9
N.A.
69.3
64.3
56.2
58.3
N.A.
38.8
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
0
6.6
N.A.
6.6
6.6
6.6
0
N.A.
20
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
13.3
N.A.
6.6
13.3
N.A.
20
46.6
26.6
13.3
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
10
0
0
10
10
10
10
19
0
19
10
19
% A
% Cys:
0
0
0
0
0
0
10
0
0
0
10
0
0
0
0
% C
% Asp:
10
37
10
10
10
0
10
0
0
37
10
19
0
0
0
% D
% Glu:
0
0
10
37
10
0
46
0
0
0
0
10
0
19
10
% E
% Phe:
10
0
0
0
10
0
0
19
0
10
28
0
0
10
0
% F
% Gly:
0
0
0
0
10
10
0
0
10
10
0
0
0
0
0
% G
% His:
10
0
10
0
0
0
0
0
0
0
0
10
0
10
0
% H
% Ile:
0
10
10
10
19
0
0
10
10
0
0
0
10
10
0
% I
% Lys:
10
0
0
0
10
10
0
0
0
0
10
10
0
0
0
% K
% Leu:
0
10
0
0
0
0
0
10
0
10
0
0
0
28
19
% L
% Met:
0
0
0
0
0
10
0
0
28
0
0
0
10
0
0
% M
% Asn:
10
0
10
0
0
0
0
10
0
0
10
10
0
0
0
% N
% Pro:
0
0
10
10
0
0
0
19
10
0
10
0
10
10
28
% P
% Gln:
0
0
37
0
10
0
0
0
0
10
0
0
0
10
0
% Q
% Arg:
0
10
10
10
0
0
10
0
10
0
0
37
0
0
10
% R
% Ser:
28
10
0
10
0
37
10
28
10
0
0
0
0
0
0
% S
% Thr:
10
0
0
0
0
10
10
0
0
10
0
10
10
0
10
% T
% Val:
19
10
0
10
28
19
0
0
19
0
10
0
10
0
0
% V
% Trp:
0
10
0
0
0
0
0
0
0
0
0
0
10
0
0
% W
% Tyr:
0
0
0
0
0
10
0
0
0
10
0
0
28
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _